Biblio
Found 9 results
Filters: Author is Caflisch, A. and Keyword is Amyloid Precursor Protein Secretases [Clear All Filters]
Specific inhibition of β-secretase processing of the Alzheimer disease amyloid precursor protein. Cell Reports. 14(9):2127-2141.
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2016. Dynamics in the active site of β-secretase: A network analysis of atomistic simulations. Biochemistry. 50(43):9328-9339.
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2011. Library screening by fragment-based docking. Journal of Molecular Recognition. 23(2):183-193.
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2010. On the orientation of the catalytic dyad in aspartic proteases. Proteins. 78(6):1575-1582.
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2010. Automatic and efficient decomposition of two-dimensional structures of small molecules for fragment-based high-throughput docking. Journal of Medicinal Chemistry. 49(25):7384-7392.
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2006. In silico discovery of beta-secretase inhibitors. Journal of the American Chemical Society. 128(16):5436-5443.
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2006. Discovery of cell-permeable non-peptide inhibitors of beta-secretase by high-throughput docking and continuum electrostatics calculations. Journal of Medicinal Chemistry. 48(16):5108-5111.
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2005. Functional plasticity in the substrate binding site of beta-secretase. Structure. 13(10):1487-1498.
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2005. Efficient evaluation of binding free energy using continuum electrostatics solvation. Journal of Medicinal Chemistry. 47(23):5791-5797.
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2004.